Gene Duplication

Liang H, Plazonic KR, Chen J, Li WH, Fernández A. Protein under-wrapping causes dosage sensitivity and decreases gene duplicability. PLoS Genet. 2008 Jan;4(1):e11.

Prachumwat, A. and W-H Li. Gene number expansion and contraction in vertebrate genomes with respect to invertebrate genomes. Genome Res. 2007 18(2):221-32.

Liang, H. and W.-H. Li (2007) Gene essentiality, gene duplicability and protein connectivity in human and mouse. Trends Genet. 23(8): 375-378.

Chen, C.C., W.-H. Li and H.M. Sung (2007) Patterns of internal gene duplication in the course of metazoan evolution. Gene 396:59-65.

Lin, Y.-S., J.-K. Hwang, and W.-H. Li (2006) Protein complexity, gene duplicability, and gene dispensability in the yeast genome. Gene 387: 109-117.

Lin, Y.-S., J. K. Byrnes, J.-K. Hwang, and W.-H. Li (2006)  Codon usage bias versus gene conversion in the evolution of yeast duplicate genes. Proc. Natl. Acad. Sci. USA. 103: 14412-14416.

Byrnes, J. K., G. P. Morris and W.-H. Li (2006) Reorganization of adjacent gene relationships in yeast genomes by whole genome duplication and gene deletion. Mol. Biol. Evol. 23:1136-1143.

Shiu, S.-H., J. K. Byrnes, R. Pan, P. Zhang  and W.-H. Li (2006) Role of positive selection in the retention of duplicate genes in mammalian genomes. Proc. Natl. Acad. Sci. USA. 103: 2232-2236.

Prachumwat, A. and W.-H. Li (2006) Protein function, connectivity, and duplicability in yeast. Mol. Biol. Evol. 23:30-39.

Zhang, L., H. H.S. Lu, W.-Y. Chung, J. Yang and W.-H. Li (2005) Patterns of segmental duplications in the human genome. Mol. Biol. Evol. 22: 135-141.

Zhang, P., W. Min and W.H. Li (2004) Different age distribution patterns of human, nematode and Arabidopsis duplicate genes. Gene 342: 263-268.

Yang, J. and W.H. Li (2004) Developmental constraint on gene duplicability in fruit flies and nematodes. Gene 340:237-240.

Marland, E., A. Prachumwat, N. Maltsev, Z. Gu, and W.H. Li (2004) Higher gene duplicabilities for metabolic proteins than for non-metabolic proteins in yeast and E. coli. J. Mol. Evol. 59:806-814.

Gu, Z., S. A. Rifkin, K. P. White, and W.H. Li (2004) Duplicate genes increase gene expression diversity within and between Species. Nat. Genet. 36:577-579.

Yang, J., R. Lusk and W.-H. Li (2003) Organismal complexity, protein complexity, and gene duplicability. Proc. Natl. Acad. Sci. USA. 100: 15661-15665.

Zhang, P. Z. Gu and W.-H. Li (2003) Different Evolutionary Patterns between Young Duplicate Genes in the Human Genome. Genome Biology 4:R56.1-6.

Makova, K. D. and W.-H. Li (2003) Divergence in the spatial pattern of gene expression between human duplicate genes. Genome Res. 13: 1638-1645.

Cavalcanti, A. R. O., Ricardo Ferreira, Z. Gu and W.-H. Li (2003) Patterns of gene duplication in Saccharomyces cerevisiae and Caenorhabditis elegans. J. Mol. Evol. 56:28-37.

Gu, Z., L. M. Steinmetz, X. Gu, C. Scharfe, R. W. Davis, and W.-H. Li (2003) Role of duplicate genes in genetic robustness against null mutations. Nature 421:63-66.

Gu, Z., D. Nicolae, H. H.-S Lu, and W.-H. Li (2002) Rapid divergence in expression between duplicate genes inferred from microarray data. Trend Genetics 18:609-613.

Gu, Z., A. Cavalcanti, F.-C. Chen, P. Bouman and W.-H. Li (2002) Extent of gene duplication in the genomes of Drosophila, nematode and yeast. Mol. Biol. Evol. 19:256-262.