Disclaimer:  The following information is drawn from materials prepared by candidates for promotion to associate professor in one of the scholarship-requiring tracks (RS and CS).  It is intended to illustrate activities and materials that might support promotion.  In using these materials, please note the following:

            *The Provost (and, in some cases, the President) are the University officers authorized to approve promotions.  All levels of review below these officers are advisory.

            *Only Departments are empowered to propose promotions, and the Divisional Dean is charged with transmitting such proposals to the Provost or returning them to the Department.

            *The judgment of the Department, Dean, and Provost will therefore be critical to assessing qualification for promotion.

            *Materials considered by the Department, Dean, and Provost will also (and always) include confidential evaluations obtained from outside the University.  Materials considered by the Provost will include the confidential evaluations of the Dean and Department, and those considered by the Dean will include the confidential evaluations of the Department.

            *Thus, the following materials are ONLY PART of a complete proposal for promotion, whereas promotion is based on the ENTIRE proposal.   Therefore, it should not be assumed that a record comparable to that below will necessarily result in promotion, or that a record not comparable to that below will fail to result in promotion.  The Departmental Chair is likely to be the best source of advice as to whether promotion is feasible and, when it is not, what additional activity may result in qualification for promotion.

            *This document has been prepared as a tool for use by assistant professors in the Division of the Biological Sciences.  Other individuals who may find it informative are Department Chairmen, Section Heads, Committee Chairmen, senior faculty and potential recruits.  Its intent is to help guide individuals and their departments as they think about promotion to Professor.  This document is not intended to list the elements that every promotion proposal will be expected to address.  The following information is presented for information purposes only and is not intended to create any contract or agreement, and its contents are subject to addition, deletion, and change without prior notice.

Name

Barbara L. Kee, Ph.D.

 

 

 Department of Primary Appointment:

Pathology

 

 Secondary appointments:

Committee on Immunology

Committee on Cancer Biology

Committee on Developmental Biology

DEPARTMENT: What is the candidate's field or specialization ?

lymphocyte differentiation

 LAY SUMMARY:  

Dr. KeeÕs work has focused on understanding the basic mechanisms that guide maturation of immune progenitor cells into mature functional effector cells. She has studied the three major lymphocyte lineages; B lymphocytes, which produce antibodies; T lymphocytes, which kill virally-infected cells and assist B lymphocytes; and natural killer (NK) cells, which kill virally-infected cells and tumor cells and also modulate B and T lymphocyte responses. As a postdoctoral fellow Dr. Kee developed an approach that provided her with the means to study B lymphocyte differentiation in vitro as well as in vivo. She has continued this work as an Assistant Professor, with her primary goals being to determine how lymphocyte cell fate decisions are regulated and to identify the mechanisms by which these decisions are controlled. Such understanding of normal lymphocyte development provides insight into how dysregulation leads to disease and may allow improved subclassification and prognostication of leukemias and lymphomas while guiding development of novel therapeutic approaches. Dr. KeeÕs work has led to new understanding of how programs that regulate cell fate decisions and differentiation are activated and maintained. Dr. Kee has also expanded her repertoire to include studies of T cell and NK cell development. These new lines of investigation have enhanced our appreciation of mechanisms that govern lymphocyte maturation and provided new fundamental understanding of how interactions between the multiple signaling events that are activated during development and neoplasia are coordinated.   

CURRICULUM VITAE

 

Awards and Honors

2002-2003       Leukemia Research Foundation Young Investigator Award

2003                   Named as the Raymond F. Zelko Young Investigator of the Cancer

                        Research Foundation

2004                Leukemia Research Foundation recommendation as a ÒScientist to WatchÓ

2006                University of Chicago Women in Science Mentoring Award

2006               American Association of Immunologists (AAI) Cynthia Chambers

                       Memorial-eBiosciences Junior Faculty Award

2007-2012      Associate Editor, The Journal of Immunology

 

Professional Service

Reviewer

Journals:

                              Journal of Immunology

Molecular and Cellular Biology

Cell Death and Differentiation

International Immunology

                              Oncogene

                              Blood

                              Nature Immunology

 

Grant Review/Study Sections:

National Science Foundation,  2001, 2004

Canadian Institutes for Health Research, 2004-2005

Austrian Research Foundation (FWF), 2004

Welcome Trust Scholar Award, 2005

Leukemia Research Foundation, 2005, 2006

National Institutes of Health CMI-A Study Section-Ad Hoc member, Oct. 2006,      

Feb. 2007

NIH Special Emphasis Panel, May 2007

 

Professional and Administrative Activities

2001-2002       Transgenic Animal Facility Task Force (U Chicago)           

2002-present   Transgenic Animal Facility Oversight Committee (U Chicago)

2002-2003       Co-organizer Committee on Immunology Annual Retreat

2002-2003       Committee on Immunology Curriculum Committee

2002-present   MSTP Steering Committee

2003-present   Selection Committee, Robert Priest Merit Award, Dept. of Pathology

2003-2006       Committee on Immunology Seminar Organizing Committee (Chair 2005-2006)

2002-present   Biological Sciences Division Graduate School Admissions Committee

2003-2005       Institutional Animal Care and Use Committee (IACUC)

2003                   Committee on Immunology Hematopoietic Development Website

2003-2005       Organizer, Committee on Immunology Faculty Chalk Talks

2004                   Developed University of Chicago Mouse Strain Database

2004-present   Department of Pathology Equipment Committee (Chair 2006-present)

2007-present   Molecular Biosciences Graduate School Admissions Committee

2007-present   University of Chicago Cancer Research Center, internal grant review committee

2007-2012       Associate Editor, Journal of Immunology

PRESENTATIONS

Seminars and Invited Talks

03/00   SUNY Downstate, Morse Institute, Department of Immunology (Invited)

06/00   Oklahoma Research Foundation, Oklahoma City, OK (Invited)

11/00   Boston University, Department of Immunology (Invited)

11/00   St. JudeÕs ChildrenÕs Hospital, Department of Immunology (Invited)

12/00   University of Chicago, Department of Pathology (Invited)

01/01   UC Berkeley, Molecular and Cellular Biology (Immunology) (Invited)

10/01   Committee on Immunology Retreat (U Chicago)

05/02   Committee on Cancer Biology Retreat (U Chicago)

10/02   Aegean Conference on Gene Regulation in Lymphocyte Development,

            Santorini, Greece (Invited)

12/02   University of Chicago, Hematology/Oncology Program

01/03   University of Chicago, Department of Pathology

03/03   Cold Spring Harbor Laboratory, NY (Invited)

04/03   Molecular Biology Program, Loyola University, Chicago IL (Invited)

07/04   Sidney Kimmel Cancer Center, La Jolla, CA (Invited)

09/04   Sunnybrook Medical Center, University of Toronto, Toronto CA (Invited)

10/04   Aegean Conference on Gene Regulation in Lymphocyte Development,

               Crete, Greece (Invited)

03/05   Keystone Symposium on B Lymphocyte Development, Steamboat Springs, CO. Workshop Chair and speaker (Invited)

04/05   UC San Diego, Department of Pathology (Invited)

05/05   EMBO Workshop on Notch Signaling, Rome, Italy. Short Talk. (Selected)

06/05   University of Illinois, Chicago, Department of Immunology (Invited)

07/05   FASEB Summer Conference  "Lymphocytes and the Immune System: Molecular, Cellular and Integrative Mechanisms", Tuscon, AZ. Workshop chair and speaker (Invited)

09/05   Lymphocyte Development Symposium, Lund, Sweden (Invited)

10/05   Unit of Lymphocyte Development, Institute Pasteur, Paris France. (Invited)

11/05   Albany Medical College, Albany NY (Invited)

04/06   Dept. of Microbiology and Immunology, Brody School of Medicine, Eastern Carolina University, Greenville NC (Invited)

05/05   National Institutes of Health, Laboratory of Immunology, Bethesda MD (Invited)

05/06   American Association of Immunologists (AAI) meeting: Minisymposium: Hematopoietic Stem Cells and Progenitors: Regulation of Self-Renewal and Early Lineage Restrictions. selected speaker.

06/06   Molecular and Cellular Biology (Immunology), UC Berkeley, Berkeley CA (Invited)

06/06   Division of Life Sciences, Lawrence Berkeley National Laboratory, Berkeley CA (Invited)

06/06   Institute for Cancer Genetics, Columbia University, New York NY (Invited)

06/06   Dept. of Cell Biology, Albert Einstein College of Medicine, Bronx NY (Invited)

08/06   Dept. of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx NY. (Invited)

10/06   Dept. of Immunology, University of Toronto, Toronto Canada (Invited)

12/06   Immunology and Microbiology, Northwestern University, Chicago IL. (Invited)

01/07   Dept. of Pathology and Abramson Cancer Research Center, University of Pennsylvania, Philadelphia PA (Invited)

05/07   American Association of Immunologist (AAI) meeting: Major Symposium D: Lineage Decision. Immunology 2007 (Invited Speaker)

 

Invited Chairperson

11/04   Chair of Workshop on B Lymphocyte Development/Antigen Processing and Presentation, Autumn Immunology Conference, Chicago IL.

03/05   Co-chair of Workshop on B Lymphocyte Development, Keystone Symposium on B Lymphocytes, Steamboat Springs, CO

04/05   Co-chair of block minisymposium "Transcriptional Control in Lymphocyte Development" at Experimental Biology (FASEB/American Association of Immunologists meeting), San Diego, CA.

07/05   Chair of Session "Cell Fate Specification and Gene Expression in Lymphocytes" at the FASEB summer workshop "Lymphocytes and the Immune System: Molecular, Cellular and Integrative Mechanisms". Tuscon, AZ.

09/05   Opponent for thesis defense of Emma Smith, Mikael Sigvardsson Lab, The Stem Cell Institute, Lund Sweden.

05/06   Co-chair of block minisymposium "Hematopoietic Stem Cells and Progenitors: Regulation of Self-Renewal and Early Lineage Restrictions" at Immunology 2006 (American Association of Immunologists meeting), Boston MA.

05/07   Co-chair, Major Symposium D: Lineage Decisions. Immunology 2007 (American Association of Immunologists meeting), Miami FL.