Hudson Lab Home Page
Research Interests
My research concerns primarily the analysis and interpretation of molecular variation
within and between populations. The goal is to understand the evolutionary forces that
have produced the observed patterns of variation within populations and between species.
My work is entirely theoretical, focusing on the stochastic processes relevant to
evolution in finite populations in which genetic drift, mutation, migration and selection
may all be important. Monte Carlo computer simulations and methods of statistical
inference are important aspects of the work. Much of my past work has focused on
Drosophila data, in the future it is likely that human variation will be a major focus.
Recent Publications
Kaplan, N.L., Hudson, R. R. and Iizuka, M. 1991
The coalescent process in models with selection, recombination and geographic subdivision. Genetical Research 57:83-91.
Slatkin, M. and Hudson, R. R. 1991
Pairwise comparisons of mitochondrial DNA sequences ins stable and exponentially growing populations. Genetics
Hudson, R. R., Bailey, K., Skarecky, D., Kwiatowski, J., and Ayala, F. J. 1994
Evidence for positive selection in the superoxide dismutase (Sod) region of Drosophila melanogaster. Genetics 136:1329-1340
Hudson, R. R. and Kaplan, N.L. 1995
Deletorious background selection with recombination. Genetics 141:1605-1617
Hudson, R.R. 1998
Island models and the coalescent process. J. Molecular Ecology: 7:413-418
Rich, S.M., Licht, M.C., Hudson, R.R., and Ayala, F.J. 1998
Malarias Eve: Evidence of a recent population bottleneck throughout the world populations of Plasmodium falciparum. Proc. Natl. Acal. Sci. (USA) 95:4425-4430
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